mouse ERCC3 shRNA silencing AAV

Name 
AAV-m-ERCC3-shRNA
Cat No 
shAAV-258633
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ercc3.

shAAV-258633
AAV-m-ERCC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ercc3 (excision repair cross-complementing rodent repair deficiency, complementation group 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BTF2 p89; Ercc-3; XPB
Description (Vector)
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
Gene ID
13872
Gene Name (Vector)
excision repair cross-complementing rodent repair deficiency, complementation group 3
Gene Symbol
Ercc3
ORF Size (aa)
2352
ORF Size (bp)
2352 bp
RefSeq ID
NM_133658
RefSeq Synonyms
NM_133658, BC026575, BC016595,
Species
mouse
UniGene ID
Mm.282335

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.