mouse EMR1 shRNA silencing AAV

Name 
AAV-m-EMR1-shRNA
Cat No 
shAAV-258352
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Adgre1.

shAAV-258352
AAV-m-EMR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Adgre1 (adhesion G protein-coupled receptor E1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
adhesion G protein-coupled receptor E1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; TM7LN3
Description (eCommerce)
Adhesion G protein-coupled receptor E1 is also known as F4/80. It is an orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. In mouse, F4/80 is a well-characterized and extensively referenced macrophage marker. It is also known as Ly71 and EMR1, and is part of the EGF-TM7 family. It is a 160 kDa glycoprotein that shares 68% amino acid identity with human EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1).
Description (Vector)
Could be involved in cell-cell interactions.
Gene ID
13733
Gene Name (eCommerce)
adhesion G protein-coupled receptor E1
Gene Name (Vector)
adhesion G protein-coupled receptor E1
Gene Symbol
Adgre1
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
2796
ORF Size (bp)
2796 bp
Protein Name (eCommerce)
Adhesion G protein-coupled receptor E1
RefSeq ID
NM_010130
RefSeq Synonyms
NM_010130, BC075688,
Research Areas
GPCR Signaling,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology
Species
mouse
Target Sentence
Adhesion G protein-coupled receptor E1 is also known as F4/80. It is an orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. In mouse, F4/80 is a well-characterized and extensively referenced macrophage marker. It is also known as Ly71 and EMR1, and is part of the EGF-TM7 family. It is a 160 kDa glycoprotein that shares 68% amino acid identity with human EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1).
UniGene ID
Mm.2254
UniProt ID (eCommerce)
Q61549

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.