mouse ELMO1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Elmo1.
shAAV-258291
AAV-m-ELMO1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Elmo1 (engulfment and cell motility 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330578D22Rik; C230095H21Rik; CED-12
Description (Vector)
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Gene ID
140580
Gene Name (Vector)
engulfment and cell motility 1
Gene Symbol
Elmo1
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_080288
RefSeq Synonyms
NM_198093, NM_080288, BC031782,
Species
mouse
UniGene ID
Mm.342392
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.