human SYP shRNA silencing AAV

Name
AAV-h-SYP-shRNA

Cat No
shAAV-224828

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SYP.

shAAV-224828

AAV-h-SYP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SYP (synaptophysin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MRX96; MRXSYP

Description (Vector)

SYP encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

Gene ID

6855

Gene Name (Vector)

synaptophysin

Gene Symbol

SYP

HGNC ID

HGNC:11506

ORF Size (aa)

942

RefSeq ID

NM_003179

RefSeq Synonyms

NM_003179, BC064550,

Species

human

UniGene ID

Hs.632804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.