human ST3GAL6 shRNA silencing AAV

Cat. No: shAAV-224462

Availability: 4-5 weeks

Name: AAV-h-ST3GAL6-shRNA

This is an AAV expressing shRNA for silencing of Human ST3GAL6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ST3GAL6
Gene Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Gene ID: 10402
Gene Synonyms: SIAT10; ST3GALVI
ORF Size: 996 bp
RefSeq#: NM_006100
Gene Description: ST3GAL6 is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UniGene ID: Hs.148716
HGNC ID: HGNC:18080