human SRD5A1 shRNA silencing AAV

Name
AAV-h-SRD5A1-shRNA

Cat No
shAAV-224313

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SRD5A1.

shAAV-224313

AAV-h-SRD5A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SRD5A1 (steroid 5 alpha-reductase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

S5AR 1

Description (Vector)

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).(supplied by OMIM, Mar 2008)

Gene ID

6715

Gene Name (Vector)

steroid 5 alpha-reductase 1

Gene Symbol

SRD5A1

HGNC ID

HGNC:11284

ORF Size (aa)

780

RefSeq ID

NM_001047

RefSeq Synonyms

NM_001324323, NM_001324322, NM_001047, BC008673, BC007033,

Species

human

UniGene ID

Hs.552

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.