human SNCAIP shRNA silencing AAV

Name 
AAV-h-SNCAIP-shRNA
Cat No 
shAAV-223825
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SNCAIP.

shAAV-223825
AAV-h-SNCAIP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNCAIP (synuclein alpha interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Sph1; SYPH1
Description (Vector)
SNCAIP encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.
Gene ID
9627
Gene Name (Vector)
synuclein alpha interacting protein
Gene Symbol
SNCAIP
HGNC ID
HGNC:11139
ORF Size (aa)
1812
ORF Size (bp)
1812 bp
RefSeq ID
NM_005460
RefSeq Synonyms
NM_005460, NM_001308109, NM_001308108, NM_001308107, NM_001308106, NM_001308105, NM_001308100, NM_001242935, BC094759, BC040552, BC033743,
Species
human
UniGene ID
Hs.426463

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.