human RSU1 shRNA silencing AAV

Name
AAV-h-RSU1-shRNA

Cat No
shAAV-222073

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RSU1.

shAAV-222073

AAV-h-RSU1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RSU1 (Ras suppressor protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ras suppressor protein 1; ras suppressor protein 1 variant 1; ras suppressor protein 1 variant 2; ras suppressor protein 1 variant 3; ras suppressor protein 1 variant 5; RSP-1; rsu-1

Description (eCommerce)

Ras suppressor protein 1 (RSU1) encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, RSU1 was initially isolated based on its ability to inhibit v-Ras transformation [taken from NCBI Entrez Gene (Gene ID: 6251)].

Description (Vector)

RSU1 encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors.

Gene ID

6251

Gene Name (eCommerce)

Ras suppressor protein 1

Gene Name (Vector)

Ras suppressor protein 1

Gene Symbol

RSU1

HGNC ID

HGNC:10464

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

834

Protein Name (eCommerce)

Ras suppressor protein 1

RefSeq ID

NM_012425

RefSeq Synonyms

NM_152724, NM_012425, BC015644, BC008691, BC005993,

Research Areas

Cytoskeleton,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology

Species

human

Target Sentence

Ras suppressor protein 1 (RSU1) encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, RSU1 was initially isolated based on its ability to inhibit v-Ras transformation [taken from NCBI Entrez Gene (Gene ID: 6251)].

UniGene ID

Hs.524161

UniProt ID (eCommerce)

Q15404

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.