human RPLP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RPLP2.
shAAV-221783
AAV-h-RPLP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RPLP2 (ribosomal protein lateral stalk subunit P2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D11S2243E; LP2; P2; RPP2
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6181
Gene Name (Vector)
ribosomal protein lateral stalk subunit P2
Gene Symbol
RPLP2
HGNC ID
HGNC:10377
ORF Size (aa)
348
RefSeq ID
NM_001004
RefSeq Synonyms
NM_001004, BC062314, BC007573, BC005920, BC005354,
Species
human
UniGene ID
Hs.437594
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.