human RPL15 shRNA silencing AAV

Name 
AAV-h-RPL15-shRNA
Cat No 
shAAV-221605
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPL15.

shAAV-221605
AAV-h-RPL15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPL15 (ribosomal protein L15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
60S ribosomal protein L15; DBA12; EC45; L15; large ribosomal subunit protein eL15; RPL10; RPLY10; RPYL10
Description (eCommerce)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL15 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6138)].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Alternate splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6138
Gene Name (eCommerce)
ribosomal protein L15
Gene Name (Vector)
ribosomal protein L15
Gene Symbol
RPL15
HGNC ID
HGNC:10306
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
438
Protein Name (eCommerce)
60S ribosomal protein L15
RefSeq ID
NM_002948
RefSeq Synonyms
NM_002948, NM_001253384, NM_001253383, NM_001253382, NM_001253380, NM_001253379, BC081565, BC071672, BC070328, BC068198, BC014837,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL15 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6138)].
UniGene ID
Hs.381219
UniProt ID (eCommerce)
P61313

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.