human ROBO2 shRNA silencing AAV

Name
AAV-h-ROBO2-shRNA

Cat No
shAAV-221470

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ROBO2.

shAAV-221470

AAV-h-ROBO2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ROBO2 (roundabout guidance receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SAX3

Description (Vector)

ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

6092

Gene Name (Vector)

roundabout guidance receptor 2

Gene Symbol

ROBO2

HGNC ID

HGNC:10250

ORF Size (aa)

4137

ORF Size (bp)

4137 bp

RefSeq ID

NM_002942

RefSeq Synonyms

NM_002942, NM_001290065, NM_001290040, NM_001290039, NM_001128929, BC146772,

Species

human

UniGene ID

Hs.13305

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.