human ROBLD3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LAMTOR2.
shAAV-221464
AAV-h-ROBLD3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ENDAP; HSPC003; MAPBPIP; MAPKSP1AP; p14; Ragulator2; ROBLD3
Description (Vector)
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
28956
Gene Name (Vector)
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Gene Symbol
LAMTOR2
HGNC ID
HGNC:29796
ORF Size (aa)
378
RefSeq ID
NM_014017
RefSeq Synonyms
NM_014017, NM_001145264, BC024190,
Species
human
UniGene ID
Hs.632483
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.