human RNPS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNPS1.
shAAV-221461
AAV-h-RNPS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNPS1 (RNA binding protein with serine rich domain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E5.1
Description (Vector)
RNPS1 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein.
Gene ID
10921
Gene Name (Vector)
RNA binding protein with serine rich domain 1
Gene Symbol
RNPS1
HGNC ID
HGNC:10080
ORF Size (aa)
918
RefSeq ID
NM_006711
RefSeq Synonyms
NM_080594, NM_006711, NM_001286627, NM_001286626, NM_001286625, BC108316, BC001838, BC001659,
Species
human
UniGene ID
Hs.355643
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.