human RNF6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNF6.
shAAV-221438
AAV-h-RNF6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNF6 (ring finger protein 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Gene ID
6049
Gene Name (Vector)
ring finger protein 6
Gene Symbol
RNF6
HGNC ID
HGNC:10069
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_005977
RefSeq Synonyms
NM_183045, NM_183044, NM_183043, NM_005977, BC034688,
Species
human
UniGene ID
Hs.136885
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.