human RNF181 shRNA silencing AAV

Name
AAV-h-RNF181-shRNA

Cat No
shAAV-221382

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RNF181.

shAAV-221382

AAV-h-RNF181-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RNF181 (ring finger protein 181). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSPC238

Description (Vector)

RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 (PubMed 18331836)).(supplied by OMIM, Dec 2008)

Gene ID

51255

Gene Name (Vector)

ring finger protein 181

Gene Symbol

RNF181

HGNC ID

HGNC:28037

ORF Size (aa)

462

RefSeq ID

NM_016494

RefSeq Synonyms

NM_016494, BC002803,

Species

human

UniGene ID

Hs.356187

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.