human RNF125 shRNA silencing AAV

Name 
AAV-h-RNF125-shRNA
Cat No 
shAAV-221341
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RNF125.

shAAV-221341
AAV-h-RNF125-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RNF125 (ring finger protein 125). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TNORS; TRAC-1; TRAC1
Description (Vector)
RNF125 encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Gene ID
54941
Gene Name (Vector)
ring finger protein 125
Gene Symbol
RNF125
HGNC ID
HGNC:21150
ORF Size (aa)
699
RefSeq ID
NM_017831
RefSeq Synonyms
NM_017831, BC012021,
Species
human
UniGene ID
Hs.633703

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.