human RGS11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RGS11.
shAAV-221109
AAV-h-RGS11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RGS11 (regulator of G-protein signaling 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RS11
Description (Vector)
RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Gene ID
8786
Gene Name (Vector)
regulator of G-protein signaling 11
Gene Symbol
RGS11
HGNC ID
HGNC:9993
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
RefSeq ID
NM_003834
RefSeq Synonyms
NM_183337, NM_003834, NM_001286486, NM_001286485, BC153019, BC148399, BC141803,
Species
human
UniGene ID
Hs.65756
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.