human RFXAP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RFXAP.
shAAV-221078
AAV-h-RFXAP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RFXAP (regulatory factor X associated protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
Gene ID
5994
Gene Name (Vector)
regulatory factor X associated protein
Gene Symbol
RFXAP
HGNC ID
HGNC:9988
ORF Size (aa)
819
ORF Size (bp)
819 bp
RefSeq ID
NM_000538
RefSeq Synonyms
NM_000538, BC026088,
Species
human
UniGene ID
Hs.24422
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.