human RDM1 shRNA silencing AAV

Name 
AAV-h-RDM1-shRNA
Cat No 
shAAV-220970
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RDM1.

shAAV-220970
AAV-h-RDM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RDM1 (RAD52 motif containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RAD52B
Description (Vector)
RDM1 encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.
Gene ID
201299
Gene Name (Vector)
RAD52 motif containing 1
Gene Symbol
RDM1
HGNC ID
HGNC:19950
ORF Size (aa)
855
RefSeq ID
NM_145654
RefSeq Synonyms
NM_145654, NM_001330194, NM_001163130, NM_001163125, NM_001163124, NM_001163122, NM_001163121, NM_001163120, NM_001034836, BC127190, BC038301,
Species
human
UniGene ID
Hs.194411

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.