human RAPSN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RAPSN.
shAAV-220745
AAV-h-RAPSN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RAPSN (receptor associated protein of the synapse). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMS11; CMS4C; FADS; RAPSYN; RNF205
Description (Vector)
RAPSN encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5913
Gene Name (Vector)
receptor associated protein of the synapse
Gene Symbol
RAPSN
HGNC ID
HGNC:9863
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_005055
RefSeq Synonyms
NM_032645, NM_005055, BC004196,
Species
human
UniGene ID
Hs.81218
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.