human RAD1 shRNA silencing AAV

Name
AAV-h-RAD1-shRNA

Cat No
shAAV-220631

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RAD1.

shAAV-220631

AAV-h-RAD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAD1 (RAD1 checkpoint DNA exonuclease). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HRAD1; REC1

Description (Vector)

RAD1 encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Gene ID

5810

Gene Name (Vector)

RAD1 checkpoint DNA exonuclease

Gene Symbol

RAD1

HGNC ID

HGNC:9806

ORF Size (aa)

849

RefSeq ID

NM_002853

RefSeq Synonyms

NM_002853, BC037857, BC009804, BC006837,

Species

human

UniGene ID

Hs.38114

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.