human PTS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTS.
shAAV-220371
AAV-h-PTS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTS (6-pyruvoyltetrahydropterin synthase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PTPS
Description (Vector)
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
Gene ID
5805
Gene Name (Vector)
6-pyruvoyltetrahydropterin synthase
Gene Symbol
PTS
HGNC ID
HGNC:9689
ORF Size (aa)
438
RefSeq ID
NM_000317
RefSeq Synonyms
NM_000317, BC018029, BC009686,
Species
human
UniGene ID
Hs.503860
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.