human PTPRN2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTPRN2.
shAAV-220356
AAV-h-PTPRN2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTPRN2 (protein tyrosine phosphatase, receptor type N2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2
Description (Vector)
PTPRN2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Gene ID
5799
Gene Name (Vector)
protein tyrosine phosphatase, receptor type N2
Gene Symbol
PTPRN2
HGNC ID
HGNC:9677
ORF Size (aa)
1902
ORF Size (bp)
1902 bp
RefSeq ID
NM_002847
RefSeq Synonyms
NM_130843, NM_130842, NM_002847, NM_001308268, NM_001308267, BC071570, BC034040,
Species
human
UniGene ID
Hs.716042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.