human PTPN4 shRNA silencing AAV

Name
AAV-h-PTPN4-shRNA

Cat No
shAAV-220324

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PTPN4.

shAAV-220324

AAV-h-PTPN4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTPN4 (protein tyrosine phosphatase, non-receptor type 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MEG; PTPMEG; PTPMEG1

Description (Vector)

PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.

Gene ID

5775

Gene Name (Vector)

protein tyrosine phosphatase, non-receptor type 4

Gene Symbol

PTPN4

HGNC ID

HGNC:9656

ORF Size (aa)

2781

ORF Size (bp)

2781 bp

RefSeq ID

NM_002830

RefSeq Synonyms

NM_002830, BC010674,

Species

human

UniGene ID

Hs.469809

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.