human PTGIR shRNA silencing AAV

Name 
AAV-h-PTGIR-shRNA
Cat No 
shAAV-220250
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTGIR.

shAAV-220250
AAV-h-PTGIR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTGIR (prostaglandin I2 (prostacyclin) receptor (IP)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IP; PRIPR
Description (Vector)
PTGIR is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
Gene ID
5739
Gene Name (Vector)
prostaglandin I2 (prostacyclin) receptor (IP)
Gene Symbol
PTGIR
HGNC ID
HGNC:9602
ORF Size (aa)
1161
ORF Size (bp)
1161 bp
RefSeq ID
NM_000960
RefSeq Synonyms
NM_000960, BC110342, BC075814,
Species
human
UniGene ID
Hs.458324

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.