human PTGDR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTGDR.
shAAV-220233
AAV-h-PTGDR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTGDR (prostaglandin D2 receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AS1; ASRT1; DP; DP1; PTGDR1
Description (Vector)
PTGDR is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
Gene ID
5729
Gene Name (Vector)
prostaglandin D2 receptor
Gene Symbol
PTGDR
HGNC ID
HGNC:9591
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_000953
RefSeq Synonyms
NM_001281469, NM_000953, BC040968,
Species
human
UniGene ID
Hs.306831
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.