human PTCRA shRNA silencing AAV

Name
AAV-h-PTCRA-shRNA

Cat No
shAAV-220219

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PTCRA.

shAAV-220219

AAV-h-PTCRA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTCRA (pre T-cell antigen receptor alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PT-ALPHA; PTA

Description (Vector)

PTCRA is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.

Gene ID

171558

Gene Name (Vector)

pre T-cell antigen receptor alpha

Gene Symbol

PTCRA

HGNC ID

HGNC:21290

ORF Size (aa)

846

RefSeq ID

NM_138296

RefSeq Synonyms

NM_138296, NM_001243170, NM_001243169, NM_001243168, BC153829, BC100774, BC100773, BC100772, BC100771, BC069336,

Species

human

UniGene ID

Hs.169002

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.