human MGLL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MGLL.
shAAV-215424
AAV-h-MGLL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MGLL (monoglyceride lipase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HU-K5; HUK5; MAGL; MGL
Description (Vector)
MGLL encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
11343
Gene Name (Vector)
monoglyceride lipase
Gene Symbol
MGLL
HGNC ID
HGNC:17038
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_007283
RefSeq Synonyms
NM_007283, NM_001256585, NM_001003794, BC006230, BC000551,
Species
human
UniGene ID
Hs.277035
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.