human FUK shRNA silencing AAV

Name
AAV-h-FUK-shRNA

Cat No
shAAV-209401

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human FUK.

shAAV-209401

AAV-h-FUK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FUK (fucokinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110046B12Rik

Description (Vector)

FUK belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.

Gene ID

197258

Gene Name (Vector)

fucokinase

Gene Symbol

FUK

HGNC ID

HGNC:29500

ORF Size (aa)

3255

ORF Size (bp)

3255 bp

RefSeq ID

NM_145059

RefSeq Synonyms

NM_145059, BC032542,

Species

human

UniGene ID

Hs.7907

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.