human FOXA2 shRNA silencing AAV

Name 
AAV-h-FOXA2-shRNA
Cat No 
shAAV-209226
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FOXA2.

shAAV-209226
AAV-h-FOXA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FOXA2 (forkhead box A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HNF3B; TCF3B
Description (Vector)
FOXA2 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Gene ID
3170
Gene Name (Vector)
forkhead box A2
Gene Symbol
FOXA2
HGNC ID
HGNC:5022
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
RefSeq ID
NM_021784
RefSeq Synonyms
NM_153675, NM_021784, BC011780,
Species
human
UniGene ID
Hs.155651

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.