human FGD3 shRNA silencing AAV

Name
AAV-h-FGD3-shRNA

Cat No
shAAV-208935

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FGD3.

shAAV-208935

AAV-h-FGD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGD3 (FYVE, RhoGEF and PH domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

faciogenital dysplasia 3; FGD1 family, member 3; FYVE, RhoGEF and PH domain-containing protein 3; ZFYVE5; zinc finger FYVE domain-containing protein 5

Description (eCommerce)

FYVE, RhoGEF and PH domain-containing protein 3 is the product of gene FGD3. This protein promotes the formation of filopodia and plays a role in regulating the actin cytoskeleton and cell shape [taken from UniProtKB (Entry: Q5JSP0)].

Gene ID

89846

Gene Name (eCommerce)

FYVE, RhoGEF and PH domain containing 3

Gene Name (Vector)

FYVE, RhoGEF and PH domain containing 3

Gene Symbol

FGD3

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2178

ORF Size (bp)

2178 bp

Protein Name (eCommerce)

FYVE, RhoGEF and PH domain-containing protein 3

RefSeq ID

NM_033086

RefSeq Synonyms

NM_033086, NM_001286993, NM_001083536, BC111054, BC032429,

Research Areas

Apoptosis,Cytoskeleton,Golgi Apparatus,GPCR Signaling,Neurobiology,NGF Signaling,Signal Transduction,Zinc-finger

Research Areas (Faceted)

signal_transduction,cell_biology,neurobiology,signal_transduction,cell_biology

Species

human

Target Sentence

FYVE, RhoGEF and PH domain-containing protein 3 is the product of gene FGD3. This protein promotes the formation of filopodia and plays a role in regulating the actin cytoskeleton and cell shape [taken from UniProtKB (Entry: Q5JSP0)].

UniGene ID

Hs.411081

UniProt ID (eCommerce)

Q5JSP0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.