human FBXO28 shRNA silencing AAV

Name 
AAV-h-FBXO28-shRNA
Cat No 
shAAV-208797
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FBXO28.

shAAV-208797
AAV-h-FBXO28-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FBXO28 (F-box protein 28). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CENP-30; centromere protein 30; F-box only protein 28; Fbx28
Description (eCommerce)
FBXO28 (F-box only protein 28) is a member of the the F-box protein family. Members of this family are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin, and F-box proteins, act as protein-ubiquitin ligases. The function of FBXO28 has not been characterized.
Description (Vector)
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
Gene ID
23219
Gene Name (eCommerce)
F-box protein 28
Gene Name (Vector)
F-box protein 28
Gene Symbol
FBXO28
HGNC ID
HGNC:29046
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1107
ORF Size (bp)
1107 bp
Protein Name (eCommerce)
F-box only protein 28
RefSeq ID
NM_015176
RefSeq Synonyms
NM_015176, NM_001136115, BC031576,
Research Areas
Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
FBXO28 (F-box only protein 28) is a member of the the F-box protein family. Members of this family are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin, and F-box proteins, act as protein-ubiquitin ligases. The function of FBXO28 has not been characterized.
UniGene ID
Hs.64691
UniProt ID (eCommerce)
Q9NVF7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.