human FAM12A shRNA silencing AAV

Name 
AAV-h-FAM12A-shRNA
Cat No 
shAAV-208381
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EDDM3A.

shAAV-208381
AAV-h-FAM12A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EDDM3A (epididymal protein 3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EP3A; FAM12A; HE3-ALPHA; HE3A; HE3ALPHA; RAM1
Description (Vector)
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.
Gene ID
10876
Gene Name (Vector)
epididymal protein 3A
Gene Symbol
EDDM3A
HGNC ID
HGNC:16978
ORF Size (aa)
444
RefSeq ID
NM_006683
RefSeq Synonyms
NM_006683, BC106712, BC106711, BC098356, BC098164, BC096731, BC096698, BC069407,
Species
human
UniGene ID
Hs.304757

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.