human EXOG shRNA silencing AAV

Name
AAV-h-EXOG-shRNA

Cat No
shAAV-208183

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human EXOG.

shAAV-208183

AAV-h-EXOG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EXOG (exo/endonuclease G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB

Description (Vector)

EXOG encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

Gene ID

9941

Gene Name (Vector)

exo/endonuclease G

Gene Symbol

EXOG

HGNC ID

HGNC:3347

ORF Size (aa)

687

ORF Size (bp)

687 bp

RefSeq ID

NM_005107

RefSeq Synonyms

NM_005107, NM_001318959, NM_001318958, NM_001318957, NM_001318956, NM_001318955, NM_001318954, NM_001145464, BC104213, BC104212,

Species

human

UniGene ID

Hs.517897

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.