human ERP29 shRNA silencing AAV

Name 
AAV-h-ERP29-shRNA
Cat No 
shAAV-208097
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ERP29.

shAAV-208097
AAV-h-ERP29-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ERP29 (endoplasmic reticulum protein 29). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C12orf8; endoplasmic reticulum lumenal protein ERp28; endoplasmic reticulum resident protein 28; endoplasmic reticulum resident protein 29; endoplasmic reticulum resident protein 31; epididymis secretory protein Li 107; ERp28; ERp29; ERp31; HEL-S-107; PDIA9; PDI-DB; protein disulfide isomerase family A, member 9
Description (eCommerce)
Endoplasmic reticulum resident protein 29 (ERP29) is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER [taken from NCBI Entrez Gene (Gene ID: 10961)].
Description (Vector)
ERP29 encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
10961
Gene Name (eCommerce)
endoplasmic reticulum protein 29
Gene Name (Vector)
endoplasmic reticulum protein 29
Gene Symbol
ERP29
HGNC ID
HGNC:13799
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
786
ORF Size (bp)
786 bp
Protein Name (eCommerce)
Endoplasmic reticulum resident protein 29
RefSeq ID
NM_006817
RefSeq Synonyms
NM_006817, NM_001034025, BC101495, BC101493,
Research Areas
Protein Folding,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Endoplasmic reticulum resident protein 29 (ERP29) is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER [taken from NCBI Entrez Gene (Gene ID: 10961)].
UniGene ID
Hs.75841
UniProt ID (eCommerce)
P30040

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.