human ERN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ERN1.
shAAV-208088
AAV-h-ERN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ERN1 (endoplasmic reticulum to nucleus signaling 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hIRE1p; IRE1; IRE1a; IRE1P
Description (Vector)
ERN1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.
Gene ID
2081
Gene Name (Vector)
endoplasmic reticulum to nucleus signaling 1
Gene Symbol
ERN1
HGNC ID
HGNC:3449
ORF Size (aa)
2934
ORF Size (bp)
2934 bp
RefSeq ID
NM_001433
RefSeq Synonyms
NM_001433, BC130407, BC130405,
Species
human
UniGene ID
Hs.700027
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.