human EMG1 shRNA silencing AAV

Name
AAV-h-EMG1-shRNA

Cat No
shAAV-207874

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human EMG1.

shAAV-207874

AAV-h-EMG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EMG1 (EMG1, N1-specific pseudouridine methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C2F; Grcc2f; NEP1

Description (Vector)

EMG1 encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome.

Gene ID

10436

Gene Name (Vector)

EMG1, N1-specific pseudouridine methyltransferase

Gene Symbol

EMG1

HGNC ID

HGNC:16912

ORF Size (aa)

735

ORF Size (bp)

735 bp

RefSeq ID

NM_006331

RefSeq Synonyms

NM_006331, NM_001320049, BC055314,

Species

human

UniGene ID

Hs.558447

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.