human EIF3E shRNA silencing AAV

Name 
AAV-h-EIF3E-shRNA
Cat No 
shAAV-207745
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EIF3E.

shAAV-207745
AAV-h-EIF3E-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EIF3E (eukaryotic translation initiation factor 3 subunit E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
eIF-3 p48; eIF3e; eIF3-p46; EIF3-P48; EIF3S6; eukaryotic translation initiation factor 3 subunit 6; eukaryotic translation initiation factor 3 subunit E; eukaryotic translation initiation factor 3 subunit E isoform 2 transcript; eukaryotic translation initiation factor 3, subunit 6 (48kD); eukaryotic translation initiation factor 3, subunit 6 48kDa; INT6; mammary tumor-associated protein INT6; murine mammary tumor integration site 6 (oncogene homolog); viral integration site protein INT-6 homolog
Description (eCommerce)
eIF3E (eukaryotic translation initiation factor 3, subunit E) is also known as INT6 (viral integration site protein INT-6 homolog). eIF3e is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex which is required for several steps in the initiation of protein synthesis.
Gene ID
3646
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit E
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit E
Gene Symbol
EIF3E
HGNC ID
HGNC:3277
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit E
RefSeq ID
NM_001568
RefSeq Synonyms
NM_001568, BC021679, BC017887, BC016706, BC008419, BC000734,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,mRNA Binding,RNA Processing,RNA Transport,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation,infectious_disease,metabolism
Species
human
Target Sentence
eIF3E (eukaryotic translation initiation factor 3, subunit E) is also known as INT6 (viral integration site protein INT-6 homolog). eIF3e is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex which is required for several steps in the initiation of protein synthesis.
UniGene ID
Hs.405590
UniProt ID (eCommerce)
P60228

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.