human CLIP1 shRNA silencing AAV

Name 
AAV-h-CLIP1-shRNA
Cat No 
shAAV-205459
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLIP1.

shAAV-205459
AAV-h-CLIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLIP1 (CAP-Gly domain containing linker protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAP-Gly domain-containing linker protein 1; CLIP; CLIP170; CLIP-170; CYLN1; cytoplasmic linker protein 1; cytoplasmic linker protein 170 alpha-2; cytoplasmic linker protein CLIP-170; Reed-Sternberg intermediate filament-associated protein; Restin; restin (Reed-Steinberg cell-expressed intermediate filament-associated protein); RSN
Description (eCommerce)
CLIP-170 (cytoplasmic linker protein 170) is a microtubule plus end binding protein (+TIPs) that plays a role in multimerizing tubulin and the formation of kinetochore-microtubule attachments.
Description (Vector)
CLIP1 links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
6249
Gene Name (eCommerce)
CAP-Gly domain containing linker protein 1
Gene Name (Vector)
CAP-Gly domain containing linker protein 1
Gene Symbol
CLIP1
HGNC ID
HGNC:10461
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4179
ORF Size (bp)
4179 bp
Protein Name (eCommerce)
CAP-Gly domain-containing linker protein 1
RefSeq ID
NM_002956
RefSeq Synonyms
NM_198240, NM_002956, NM_001247997, BC126305, BC117209, BC114213,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,mTOR Signaling,Neurobiology,Neurodevelopment,Signal Transduction,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,neurobiology,signal_transduction
Species
human
Target Sentence
CLIP-170 (cytoplasmic linker protein 170) is a microtubule plus end binding protein (+TIPs) that plays a role in multimerizing tubulin and the formation of kinetochore-microtubule attachments.
UniGene ID
Hs.524809
UniProt ID (eCommerce)
P30622

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.