mouse RHOB Adenovirus
This is an Adenovirus expressing Mouse Rhob.
ADV-270530
Ad-m-RHOB
Ready-to-use Adenovirus expressing Mouse Rhob (ras homolog family member B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA017882; Arh6; Arhb
Description (Vector)
Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Gene ID
11852
Gene Name (Vector)
ras homolog family member B
Gene Symbol
Rhob
ORF Size (aa)
591
RefSeq ID
NM_007483
RefSeq Synonyms
NM_007483, BC110992, BC018275,
Species
mouse
UniGene ID
Mm.687
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.