mouse BNIP3 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-254045
Availability:
Immediate
Name:
Ad-m-BNIP3
This is an Adenovirus expressing Mouse Bnip3.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Bnip3
- Gene Name
- BCL2/adenovirus E1B interacting protein 3
- Gene ID
- 12176
- Gene Synonyms
- Nip3
- ORF Size
- 564 bp
- RefSeq#
- BC046603
- Gene Description
- Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.
- UniGene ID
- Mm.378890
Product Citations
This product is referenced in the following publications:
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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