human OBFC2A Adenovirus

Name 
Ad-h-OBFC2A
Cat No 
ADV-217318
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human OBFC2A.

ADV-217318
Ad-h-OBFC2A

Ready-to-use Adenovirus expressing Human NABP1 (nucleic acid binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hSSB2; Nucleic acid-binding protein 1; OBFC2A; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2; SSB2
Description (eCommerce)
OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.
Description (Vector)
Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 (PubMed 18449195)).(supplied by OMIM, Jun 2008)
Gene ID
64859
Gene Name (eCommerce)
nucleic acid binding protein 1
Gene Name (Vector)
nucleic acid binding protein 1
Gene Symbol
NABP1
HGNC ID
HGNC:26232
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
615
Protein Name (eCommerce)
SOSS complex subunit B2
RefSeq ID
NM_001031716
RefSeq Synonyms
NM_001254736, NM_001031716, BC107723, BC017114,
Research Areas
Cell Cycle,DNA Damage/Repair,RNA Binding
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.
UniGene ID
Hs.591610
UniProt ID (eCommerce)
Q96AH0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.