human NUP153 Adenovirus
This is an Adenovirus expressing Human NUP153.
ADV-217234
Ad-h-NUP153
Ready-to-use Adenovirus expressing Human NUP153 (nucleoporin 153). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
153 kDa nucleoporin; HNUP153; N153; nuclear pore complex protein hnup153; nuclear pore complex protein Nup153; nucleoporin 153kD; nucleoporin 153kDa; nucleoporin Nup153
Description (eCommerce)
The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nup153 contains four RanBP2-type zinc fingers and an RNA binding domain. The zinc-fingers of Nup153 can bind the small GTPase, Ran. The RNA binding domain has been shown to have an affinity for single-stranded RNA.
Description (Vector)
Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.
Gene ID
9972
Gene Name (eCommerce)
nucleoporin 153
Gene Name (Vector)
nucleoporin 153
Gene Symbol
NUP153
HGNC ID
HGNC:8062
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4428
ORF Size (bp)
4428 bp
Protein Name (eCommerce)
Nuclear pore complex protein Nup153
RefSeq ID
NM_005124
RefSeq Synonyms
NM_005124, NM_001278210, NM_001278209, BC052965,
Research Areas
Cell Cycle,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,MicroRNAs in Cancer,mRNA Processing,mRNA Transport,Ribonucleoprotein Transport,RNA Processing,RNA Transport,Signal Transduction,TGF-beta Signaling,Transport,Zinc-finger
Research Areas (Faceted)
cancer,genetics,signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism,genetics,transcription_translation,cell_biology,signal_transduction,immunology,cell_biology
Species
human
Target Sentence
The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nup153 contains four RanBP2-type zinc fingers and an RNA binding domain. The zinc-fingers of Nup153 can bind the small GTPase, Ran. The RNA binding domain has been shown to have an affinity for single-stranded RNA.
UniGene ID
Hs.718703
UniProt ID (eCommerce)
P49790
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.