human NAGK Adenovirus

Name
Ad-h-NAGK

Cat No
ADV-216289

Availability
4-5 weeks

This is an Adenovirus expressing Human NAGK.

ADV-216289

Ad-h-NAGK

Ready-to-use Adenovirus expressing Human NAGK (N-acetylglucosamine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

epididymis secretory sperm binding protein; glcNAc kinase; GNK; HSA242910; N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase

Description (eCommerce)

N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals [taken from NCBI Entrez Gene (GeneID: 55577)].

Description (Vector)

NAGK encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars.

Gene ID

55577

Gene Name (eCommerce)

N-acetylglucosamine kinase

Gene Name (Vector)

N-acetylglucosamine kinase

Gene Symbol

NAGK

HGNC ID

HGNC:17174

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1035

ORF Size (bp)

1035 bp

Protein Name (eCommerce)

N-acetyl-D-glucosamine kinase

RefSeq ID

NM_017567

RefSeq Synonyms

NM_017567, NM_001330426, NM_001330425, BC005371, BC001029,

Research Areas

Kinase/Phosphatase,Metabolism/Metabolic Process

Research Areas (Faceted)

cell_biology,metabolism,signal_transduction

Species

human

Target Sentence

N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals [taken from NCBI Entrez Gene (GeneID: 55577)].

UniGene ID

Hs.7036

UniProt ID (eCommerce)

Q9UJ70

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.