human MTMR6 Adenovirus

Name 
Ad-h-MTMR6
Cat No 
ADV-216024
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MTMR6.

ADV-216024
Ad-h-MTMR6

Ready-to-use Adenovirus expressing Human MTMR6 (myotubularin related protein 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
myotubularin-related protein 6
Description (eCommerce)
Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y217].
Gene ID
9107
Gene Name (eCommerce)
myotubularin related protein 6
Gene Name (Vector)
myotubularin related protein 6
Gene Symbol
MTMR6
HGNC ID
HGNC:7453
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
Protein Name (eCommerce)
Myotubularin-related protein 6
RefSeq ID
NM_004685
RefSeq Synonyms
NM_004685, BC040012,
Research Areas
Kinase/Phosphatase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y217].
UniGene ID
Hs.643702
UniProt ID (eCommerce)
Q9Y217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.