human MED26 Adenovirus

Name 
Ad-h-MED26
Cat No 
ADV-215259
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MED26.

ADV-215259
Ad-h-MED26

Ready-to-use Adenovirus expressing Human MED26 (mediator complex subunit 26). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
activator-recruited cofactor 70 kDa component; ARC70; cofactor required for Sp1 transcriptional activation subunit 7; cofactor required for Sp1 transcriptional activation, subunit 7 (70kD); cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa; CRSP complex subunit 7; CRSP7; CRSP70; Mediator complex subunit 26; mediator of RNA polymerase II transcription subunit 26; transcriptional coactivator CRSP70
Description (eCommerce)
CRSP7 (cofactor required for Sp1 transcriptional activation, subunit 7) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes such as thyroid hormone receptor-(TR-) associated protein (TRAP) and mediator complexes. CRSP7 is also known as MED26 (mediator complex subunit 26 [taken from NCBI Entrez Gene (GeneID: 9441)].
Description (Vector)
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Gene ID
9441
Gene Name (eCommerce)
mediator complex subunit 26
Gene Name (Vector)
mediator complex subunit 26
Gene Symbol
MED26
HGNC ID
HGNC:2376
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
Protein Name (eCommerce)
Mediator of RNA polymerase II transcription subunit 26
RefSeq ID
NM_004831
RefSeq Synonyms
NM_004831, BC110430,
Research Areas
Gene Expression,Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
CRSP7 (cofactor required for Sp1 transcriptional activation, subunit 7) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes such as thyroid hormone receptor-(TR-) associated protein (TRAP) and mediator complexes. CRSP7 is also known as MED26 (mediator complex subunit 26 [taken from NCBI Entrez Gene (GeneID: 9441)].
UniGene ID
Hs.651587
UniProt ID (eCommerce)
O95402

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.