human MBTPS1 Adenovirus
This is an Adenovirus expressing Human MBTPS1.
ADV-215128
Ad-h-MBTPS1
Ready-to-use Adenovirus expressing Human MBTPS1 (membrane bound transcription factor peptidase, site 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PCSK8; S1P; SKI-1
Description (Vector)
The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein.
Gene ID
8720
Gene Name (Vector)
membrane bound transcription factor peptidase, site 1
Gene Symbol
MBTPS1
HGNC ID
HGNC:15456
ORF Size (aa)
3159
ORF Size (bp)
3159 bp
RefSeq ID
NM_003791
RefSeq Synonyms
NM_003791, BC114961, BC114555, BC026330,
Species
human
UniGene ID
Hs.75890
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.