human EXOSC6 Adenovirus
This is an Adenovirus expressing Human EXOSC6.
ADV-208194
Ad-h-EXOSC6
Ready-to-use Adenovirus expressing Human EXOSC6 (exosome component 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EAP4; hMtr3p; MTR3; Mtr3p; p11
Description (Vector)
EXOSC6 product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
Gene ID
118460
Gene Name (Vector)
exosome component 6
Gene Symbol
EXOSC6
HGNC ID
HGNC:19055
ORF Size (aa)
819
ORF Size (bp)
819 bp
RefSeq ID
NM_058219
RefSeq Synonyms
NM_058219, BC052252,
Species
human
UniGene ID
Hs.660633
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.