human CRTC1 Adenovirus

Name
Ad-h-CRTC1

Cat No
ADV-206038

Availability
4-5 weeks

This is an Adenovirus expressing Human CRTC1.

ADV-206038

Ad-h-CRTC1

Ready-to-use Adenovirus expressing Human CRTC1 (CREB regulated transcription coactivator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CREB-regulated transcription coactivator 1; Mam-2; MAML2; Mastermind-like protein 2; MECT1; mucoepidermoid carcinoma translocated protein 1; TORC1; TORC-1; Transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1

Description (eCommerce)

TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.

Gene ID

23373

Gene Name (eCommerce)

CREB regulated transcription coactivator 1

Gene Name (Vector)

CREB regulated transcription coactivator 1

Gene Symbol

CRTC1

HGNC ID

HGNC:16062

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1905

ORF Size (bp)

1905 bp

Protein Name (eCommerce)

CREB-regulated transcription coactivator 1

RefSeq ID

NM_015321

RefSeq Synonyms

NM_015321, NM_001098482, BC028050,

Research Areas

BDNF Signaling,Cancer,Host-Virus Interactions,Neurobiology,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins

Research Areas (Faceted)

cancer,cell_biology,infectious_disease,neurobiology,signal_transduction,transcription_translation

Species

human

Target Sentence

TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.

UniGene ID

Hs.371096

UniProt ID (eCommerce)

Q6UUV9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.