mouse RRAD Over-expression AAV

Name 
AAV-m-RRAD
Cat No 
AAV-271132
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rrad.

AAV-271132
AAV-m-RRAD

Ready-to-use AAV expressing Mouse Rrad (Ras-related associated with diabetes). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Rad; REM3
Description (Vector)
RRAD may play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Gene ID
56437
Gene Name (Vector)
Ras-related associated with diabetes
Gene Symbol
Rrad
ORF Size (aa)
924
RefSeq ID
NM_019662
RefSeq Synonyms
NM_019662, BC057138,
Species
mouse
UniGene ID
Mm.29467

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.